Across TCGA cell cohorts, NBPF1 mutation is significantly associated with the RNA expression of many other genes, with 142 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NBPF1-associated genes across cancer lineages are OR2M3, OBP2B, and CMA1. Each is linked with NBPF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NBPF1-to-partner and partner-to-NBPF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF1→partner) and Y-score (partner→NBPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR2M3 →	+0.015	+2.343	<.001	.006	3	3
BLOOD_Leukemia	OBP2B →	+0.021	+2.877	<.001	.002	3	3
LUNG_NSCLC_LUSC	CMA1 →	+0.044	+4.108	<.001	.005	3	2
LUNG_SCLC	H2AB1 →	+0.307	+3.132	<.001	.001	3	2
OESOPHAGUS	CCDC172 →	+0.030	+4.857	<.001	<.001	3	1
BLOOD_Myeloma	RHO →	+0.079	+3.977	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 142 associations by consensus.

Exploration

NBPF1 survival (RNA) · tumor vs normal (RNA) · all NBPF1 data types