NAA40

Across TCGA cell cohorts, NAA40 mutation is significantly associated with the mutation status of many other genes, with 1,371 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAA40-associated genes across cancer lineages are CMTM6, PACSIN2, and IL2RB. Each is linked with NAA40 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA40-to-partner and partner-to-NAA40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMTM6 grouped by NAA40-low versus NAA40-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA40→partner) and Y-score (partner→NAA40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CMTM6 →	+6.321	+6.321	.001	.001	1	2
BLOOD_Leukemia	PACSIN2 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	IL2RB →	+5.321	+5.894	.002	.002	1	2
BLOOD_Leukemia	RBBP7 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	RAB34 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	NR1H4 →	+6.321	+6.321	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,371 associations by consensus.

CMTM6 by NAA40 expression — BLOOD_Leukemia

Explore this box plot interactively →