MYO7B

Across TCGA patient cohorts, MYO7B protein abundance is significantly associated with the RNA expression of many other genes, with 4,000 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MYO7B-associated genes across cancer lineages are EHMT2-AS1, CAV1, and EPCAM. Each is linked with MYO7B in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO7B-to-partner and partner-to-MYO7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO7B versus EHMT2-AS1 in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO7B→partner) and Y-score (partner→MYO7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EHMT2-AS1 →	+0.719	+0.798	<.001	.009	3	3
PDAC	CAV1 →	-0.860	-0.678	<.001	<.001	3	3
CCRCC	EPCAM →	+0.880	+0.406	<.001	<.001	3	3
CCRCC	PLS1 →	+0.680	+0.414	.006	.001	3	3
CCRCC	EPHX2 →	+0.962	+0.582	.004	<.001	3	3
PDAC	FMO5 →	+0.788	+0.757	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,000 associations by consensus.

MYO7B vs EHMT2-AS1 — UCEC

Explore this scatter interactively →