MYH7B

Across TCGA cell cohorts, MYH7B mutation is significantly associated with the RNA expression of many other genes, with 737 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYH7B-associated genes across cancer lineages are MTNR1A, C12orf60, and IFNK. Each is linked with MYH7B in more than 1 cancer types. Because this analysis shows association rather than direction, both MYH7B-to-partner and partner-to-MYH7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTNR1A grouped by MYH7B-low versus MYH7B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH7B→partner) and Y-score (partner→MYH7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MTNR1A →	+0.282	+2.386	.004	.007	3	2
LARGE_INTESTINE	C12orf60 →	+0.602	+2.523	<.001	.003	3	2
OESOPHAGUS	IFNK →	+0.030	+3.392	<.001	.007	3	1
OESOPHAGUS	SPANXN5 →	+0.107	+3.836	.002	.004	3	1
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1
PANCREAS	TBL1Y →	+0.006	+5.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 737 associations by consensus.

MTNR1A by MYH7B expression — LARGE_INTESTINE

Explore this box plot interactively →