MYH7B

Across TCGA pan-cancer cohorts, MYH7B RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of MYH7B’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MYH7B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MYH7B is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, KICH, and THCA are the cancer types where MYH7B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYH7B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.330	<.001	10	view →
KICH	Female	All	−0.559	<.001	8	view →
THCA	All	All	−0.370	<.001	7	view →
BRCA	All	III,IV	−0.715	<.001	6	view →
KIRP	Male	All	−0.391	<.001	6	view →
HNSC	All	All	−0.548	.011	5	view →
KIRC	Male	II,III,IV	+0.184	.015	5	view →
STAD	All	II,III,IV	+0.317	.011	4	view →
LIHC	All	All	+0.295	.001	3	view →
CHOL	All	All	+0.716	.004	2	view →
PRAD	All	All	−0.276	.035	2	view →
BLCA	Male	IV	−0.524	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

MYH7B–COAD

Open the COAD breakdown →