Across TCGA patient cohorts, MTHFD2P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,874 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTHFD2P3-associated GO terms across cancer lineages are Glycosylation, Regulation of DNA-templated transcription initiation, and Base-excision repair. Each is linked with MTHFD2P3 in more than 11 cancer types. Because this analysis shows association rather than direction, both MTHFD2P3-to-partner and partner-to-MTHFD2P3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTHFD2P3→partner) and Y-score (partner→MTHFD2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Glycosylation →	+0.041	+0.169	<.001	<.001	3	12
STAD	Regulation of DNA-templated transcription initiation →	+0.057	+0.187	<.001	<.001	3	11
STAD	Base-excision repair →	+0.053	+0.189	<.001	<.001	3	11
STAD	DNA-templated transcription elongation →	+0.067	+0.185	<.001	<.001	3	11
STAD	Transcription preinitiation complex assembly →	+0.055	+0.180	<.001	<.001	3	11
TGCT	Negative regulation of cell projection organization →	+0.041	+0.086	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,874 associations by consensus.

Exploration

MTHFD2P3 survival (RNA) · tumor vs normal (RNA) · all MTHFD2P3 data types