MTHFD2P3

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MTHFD2P3 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTHFD2P3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MTHFD2P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTHFD2P3 is over-expressed in tumor.

HNSC are the cancer types where MTHFD2P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTHFD2P3 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCMaleAll+0.055.0481view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

MTHFD2P3–HNSC

Tumor-vs-normal expression box plot for MTHFD2P3 RNA in HNSC.

Open the HNSC breakdown →

Exploration