Q-omics provides the consensus-scored MTCO1P10 profile across patient tissues and cancer cell-line models. MTCO1P10 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in THYM. Among the 18 cancer types available for tumor–normal comparison, MTCO1P10 is differentially expressed in 3, with the highest sampling consensus in UCEC. Additionally, MTCO1P10 RNA expression shows 8,976 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight THYM, UCEC, and TGCT as cancer lineages where MTCO1P10 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO1P10 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO1P10 survival associations across molecular data types. MTCO1P10 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO1P10 RNA expression–survival associations across cancer types. High MTCO1P10 expression shows unfavorable associations in THYM, LUAD, SKCM and UCEC, but favorable associations in COAD and ACC. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THYM as the clearest survival context for MTCO1P10 RNA expression.
This table summarizes MTCO1P10 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO1P10. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO1P10 shows lower tumor expression in LIHC and higher tumor expression in UCEC and KICH. The UCEC box plot shows higher MTCO1P10 RNA expression in tumor versus normal tissue (log2 FC = +0.046, t-test p = .033).
This table shows molecular features associated with MTCO1P10 in patient tissues and cancer cell lines. In patient samples, MTCO1P10 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
