Across TCGA patient cohorts, MT-TR RNA expression is significantly associated with the go_rna of many other GO terms, with 5,039 significant associations in total. LGG shows the largest number of these associations.

The most reproducible MT-TR-associated GO terms across cancer lineages are Cardiolipin biosynthetic process, ATP synthesis coupled electron transport, and Cellular respiration. Each is linked with MT-TR in more than 9 cancer types. Because this analysis shows association rather than direction, both MT-TR-to-partner and partner-to-MT-TR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TR→partner) and Y-score (partner→MT-TR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Cardiolipin biosynthetic process →	+0.029	+0.133	<.001	<.001	3	10
CHOL	ATP synthesis coupled electron transport →	+0.028	+1.136	.003	.001	2	10
KIRC	Cellular respiration →	+0.016	+0.158	<.001	<.001	3	9
HNSC	Protein maturation by [4Fe-4S] cluster transfer →	+0.025	+0.210	<.001	<.001	3	9
KIRC	Respiratory electron transport chain →	+0.020	+0.169	<.001	<.001	3	8
KIRC	Proton transmembrane transport →	+0.020	+0.184	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,039 associations by consensus.

Exploration

MT-TR survival (RNA) · tumor vs normal (RNA) · all MT-TR data types