Across TCGA patient cohorts, MT-TN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,680 significant associations in total. OV shows the largest number of these associations.

The most reproducible MT-TN-associated GO terms across cancer lineages are Regulation of dephosphorylation, Negative regulation of dephosphorylation, and Golgi localization. Each is linked with MT-TN in more than 4 cancer types. Because this analysis shows association rather than direction, both MT-TN-to-partner and partner-to-MT-TN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TN→partner) and Y-score (partner→MT-TN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Regulation of dephosphorylation →	-0.022	-0.093	<.001	<.001	3	5
KIRP	Negative regulation of dephosphorylation →	-0.024	-0.167	<.001	<.001	3	5
KIRC	Golgi localization →	-0.045	-0.043	<.001	.004	3	4
KIRC	Protein K48-linked ubiquitination →	-0.029	-0.057	<.001	.004	2	5
THCA	Regulation of establishment of planar polarity →	-0.024	-0.085	<.001	<.001	3	4
KIRC	Positive regulation of lamellipodium organization →	-0.041	-0.059	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,680 associations by consensus.

Exploration

MT-TN survival (RNA) · tumor vs normal (RNA) · all MT-TN data types