Across TCGA patient cohorts, MT-TA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,667 significant associations in total. OV shows the largest number of these associations.

The most reproducible MT-TA-associated GO terms across cancer lineages are Cellular response to insulin-like growth factor stimulus, Cerebral cortex radially oriented cell migration, and Obsolete post-embryonic animal organ development. Each is linked with MT-TA in more than 4 cancer types. Because this analysis shows association rather than direction, both MT-TA-to-partner and partner-to-MT-TA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TA→partner) and Y-score (partner→MT-TA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	Cellular response to insulin-like growth factor stimulus →	-0.063	-0.703	<.001	<.001	3	5
LAML	Cerebral cortex radially oriented cell migration →	-0.027	-0.526	<.001	.001	3	5
STAD	Obsolete post-embryonic animal organ development →	-0.031	-0.462	<.001	<.001	3	5
STAD	Regulation of centriole replication →	-0.032	-0.527	<.001	<.001	3	4
STAD	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.050	-0.746	<.001	<.001	3	4
STAD	Nuclear pore organization →	-0.045	-0.579	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,667 associations by consensus.

Exploration

MT-TA survival (RNA) · tumor vs normal (RNA) · all MT-TA data types