Across TCGA patient cohorts, MT-ATP6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,616 significant associations in total. OV shows the largest number of these associations.

The most reproducible MT-ATP6-associated genes across cancer lineages are MICAL2, NLRP3, and DCBLD2. Each is linked with MT-ATP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both MT-ATP6-to-partner and partner-to-MT-ATP6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ATP6→partner) and Y-score (partner→MT-ATP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MICAL2 →	-0.834	-0.454	<.001	<.001	3	4
HNSC	NLRP3 →	-0.719	-0.355	<.001	.004	3	4
LSCC	DCBLD2 →	-0.716	-0.427	.003	<.001	3	4
OV	STAB1 →	-1.123	-0.446	<.001	.002	2	5
OV	MEIS3 →	-1.040	-0.436	<.001	.004	3	4
LSCC	RCN3 →	-1.035	-0.400	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,616 associations by consensus.

Exploration

MT-ATP6 survival (RNA) · tumor vs normal (RNA) · all MT-ATP6 data types