MSH5-SAPCD1

Across TCGA patient cohorts, MSH5-SAPCD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,160 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MSH5-SAPCD1-associated proteins across cancer lineages are TOP2A, MDC1, and RFC2. Each is linked with MSH5-SAPCD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MSH5-SAPCD1-to-partner and partner-to-MSH5-SAPCD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSH5-SAPCD1 versus TOP2A in GBM, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MSH5-SAPCD1→partner) and Y-score (partner→MSH5-SAPCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2A →	+0.902	+0.335	<.001	<.001	3	7
GBM	MDC1 →	+0.423	+0.368	<.001	<.001	3	7
HNSC	RFC2 →	+0.390	+0.208	<.001	.004	3	7
LSCC	ATAD2 →	+0.609	+0.233	<.001	<.001	3	7
GBM	SUZ12 →	+0.443	+0.307	<.001	.001	3	7
PDAC	GINS3 →	+0.949	+0.253	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,160 associations by consensus.

MSH5-SAPCD1 vs TOP2A — GBM

Explore this scatter interactively →