Across TCGA patient cohorts, MROH2A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,725 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MROH2A-associated proteins across cancer lineages are GSTM2, TOP2A, and NCOA5. Each is linked with MROH2A in more than 3 cancer types. Because this analysis shows association rather than direction, both MROH2A-to-partner and partner-to-MROH2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MROH2A→partner) and Y-score (partner→MROH2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GSTM2 →	+0.778	+0.766	<.001	.002	3	4
GBM	TOP2A →	+0.774	+0.124	<.001	<.001	3	4
GBM	NCOA5 →	+0.248	+0.092	<.001	<.001	3	4
GBM	TTK_S436 →	+1.050	+0.159	<.001	<.001	3	3
HNSC	VAMP3 →	-0.258	-0.749	.002	.004	3	3
GBM	WAS →	-0.563	-0.107	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,725 associations by consensus.

Exploration

MROH2A survival (RNA) · tumor vs normal (RNA) · all MROH2A data types