MRGPRX4

Across TCGA patient cohorts, MRGPRX4 RNA expression is significantly associated with the RNA expression of many other genes, with 8,299 significant associations in total. THYM shows the largest number of these associations.

The most reproducible MRGPRX4-associated genes across cancer lineages are MRGPRX3, MRGPRX13P, and SAA3P. Each is linked with MRGPRX4 in more than 15 cancer types. Because this analysis shows association rather than direction, both MRGPRX4-to-partner and partner-to-MRGPRX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRGPRX4 versus MRGPRX3 in SKCM, with a Pearson correlation of 0.20.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRX4→partner) and Y-score (partner→MRGPRX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MRGPRX3 →	+1.296	+0.811	<.001	<.001	3	16
UCS	MRGPRX13P →	+1.071	+0.113	<.001	<.001	3	15
UCS	SAA3P →	+0.546	+0.068	<.001	<.001	3	11
UCEC	TUBB3P1 →	+0.591	+0.086	<.001	<.001	3	9
UCS	RNA5SP528 →	+0.758	+0.053	.001	.003	2	10
TGCT	ZNF735 →	+0.540	+0.047	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,299 associations by consensus.

MRGPRX4 vs MRGPRX3 — SKCM

Explore this scatter interactively →