tubulin beta 3 class III pseudogene 1Genealiases: []
Q-omics provides the consensus-scored TUBB3P1 profile across patient tissues and cancer cell-line models. TUBB3P1 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, TUBB3P1 is differentially expressed in 7, with the highest sampling consensus in HNSC. Additionally, TUBB3P1 RNA expression shows 7,896 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight BRCA, HNSC, and THYM as cancer lineages where TUBB3P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TUBB3P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TUBB3P1 survival associations across molecular data types. TUBB3P1 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TUBB3P1 RNA expression–survival associations across cancer types. High TUBB3P1 expression shows unfavorable associations in BRCA, KIRC, SKCM and MESO, but favorable associations in COAD and UCEC. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .011). Together, the overview and detailed table identify BRCA as the clearest survival context for TUBB3P1 RNA expression.
This table summarizes TUBB3P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for TUBB3P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TUBB3P1 shows lower tumor expression in BRCA and higher tumor expression in HNSC, BLCA, LUSC, LUAD and COAD. The HNSC box plot shows higher TUBB3P1 RNA expression in tumor versus normal tissue (log2 FC = +0.147, t-test p = .012).
This table shows molecular features associated with TUBB3P1 in patient tissues and cancer cell lines. In patient samples, TUBB3P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
