MON1B

Across TCGA patient cohorts, MON1B mutation is significantly associated with the RNA expression of many other genes, with 1,766 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MON1B-associated genes across cancer lineages are TYMSOS, ZIC2, and ETFA. Each is linked with MON1B in more than 2 cancer types. Because this analysis shows association rather than direction, both MON1B-to-partner and partner-to-MON1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TYMSOS grouped by MON1B-low versus MON1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MON1B→partner) and Y-score (partner→MON1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TYMSOS →	+0.712	+3.818	<.001	<.001	3	3
UCEC	ZIC2 →	+1.354	+1.828	.001	.002	3	3
UCEC	ETFA →	+0.599	+2.523	<.001	<.001	3	3
LUSC	RPL23AP94 →	+0.082	+2.940	.009	.005	3	3
LUAD	RN7SL98P →	+0.098	+3.491	.006	.008	3	3
BLCA	SNRPCP20 →	+0.138	+4.588	.009	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,766 associations by consensus.

TYMSOS by MON1B expression — UCEC

Explore this box plot interactively →