Q-omics provides the consensus-scored TYMSOS profile across patient tissues and cancer cell-line models. TYMSOS expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in OV. Among the 18 cancer types available for tumor–normal comparison, TYMSOS is differentially expressed in 13, with the highest sampling consensus in KIRC. Additionally, TYMSOS RNA expression shows 16,180 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight OV, KIRC, and THYM as cancer lineages where TYMSOS shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TYMSOS — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TYMSOS survival associations across molecular data types. TYMSOS RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TYMSOS RNA expression–survival associations across cancer types. High TYMSOS expression shows unfavorable associations in ACC, KICH and UVM, but favorable associations in OV, KIRP and KIRC. The OV Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify OV as the clearest survival context for TYMSOS RNA expression.
This table summarizes TYMSOS tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for TYMSOS. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TYMSOS shows higher tumor expression in KIRC, BLCA, LUAD, THCA, LUSC and LIHC. The KIRC box plot shows higher TYMSOS RNA expression in tumor versus normal tissue (log2 FC = +1.613, t-test p < 0.001).
This table shows molecular features associated with TYMSOS in patient tissues and cancer cell lines. In patient samples, TYMSOS shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
