MIR4277

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR4277 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR4277-associated genes across cancer lineages are RNU1-84P, RN7SKP112, and RNA5SP508. Each is linked with MIR4277 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR4277-to-partner and partner-to-MIR4277 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-84P grouped by MIR4277-low versus MIR4277-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4277→partner) and Y-score (partner→MIR4277) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU1-84P →+0.306+5.242.003.00731
UCECRN7SKP112 →+0.250+5.186.001.00731
UCECRNA5SP508 →+0.637+5.694<.001.00331
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

RNU1-84P by MIR4277 expression — UCEC

Box plot of RNU1-84P in MIR4277-low vs MIR4277-high samples in UCEC.

Explore this box plot interactively →

Exploration