MINDY3

Across TCGA patient cohorts, MINDY3 mutation is significantly associated with the RNA expression of many other genes, with 802 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MINDY3-associated genes across cancer lineages are RNU6-1150P, MIR1283-1, and RNU6ATAC29P. Each is linked with MINDY3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MINDY3-to-partner and partner-to-MINDY3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1150P grouped by MINDY3-low versus MINDY3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MINDY3→partner) and Y-score (partner→MINDY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-1150P →	+0.465	+4.812	<.001	.003	3	2
COAD	MIR1283-1 →	+0.726	+7.741	<.001	.009	3	2
UCEC	RNU6ATAC29P →	+0.291	+2.163	.001	.002	3	2
UCEC	SNRPGP8 →	+0.103	+2.850	.001	.002	3	2
BLCA	MRGPRX8P →	+0.035	+5.229	<.001	.002	3	2
LUAD	MIR708 →	+0.646	+3.899	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 802 associations by consensus.

RNU6-1150P by MINDY3 expression — BRCA

Explore this box plot interactively →