MED18

Across TCGA patient cohorts, MED18 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,282 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED18-associated proteins across cancer lineages are RCC1, RPS6KA1, and SYF2. Each is linked with MED18 in more than 4 cancer types. Because this analysis shows association rather than direction, both MED18-to-partner and partner-to-MED18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED18 versus RCC1 in LUAD, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED18→partner) and Y-score (partner→MED18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RCC1 →	+0.313	+0.217	<.001	.004	3	5
PDAC	RPS6KA1 →	+0.395	+0.414	<.001	<.001	3	5
GBM	SYF2 →	+0.303	+0.223	<.001	<.001	3	5
GBM	YTHDF2 →	+0.281	+0.214	<.001	.003	3	5
LSCC	ARHGEF16 →	+0.388	+0.315	<.001	<.001	3	5
LSCC	PUM1 →	+0.220	+0.427	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,282 associations by consensus.

MED18 vs RCC1 — LUAD

Explore this scatter interactively →