MAST1

Across TCGA patient cohorts, MAST1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,092 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAST1-associated genes across cancer lineages are CD1D, GNG3, and NLGN3. Each is linked with MAST1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAST1-to-partner and partner-to-MAST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAST1 versus CD1D in GBM, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAST1→partner) and Y-score (partner→MAST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD1D →	-0.579	-0.349	<.001	.002	3	2
GBM	GNG3 →	+0.815	+0.450	<.001	<.001	3	2
GBM	NLGN3 →	+0.945	+0.319	.002	.004	3	2
GBM	H3P43 →	+1.122	+0.413	<.001	<.001	3	2
GBM	CACNB1 →	+0.611	+0.515	<.001	<.001	3	2
GBM	TNRC6C →	+0.463	+0.416	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,092 associations by consensus.

MAST1 vs CD1D — GBM

Explore this scatter interactively →