MAP1S

Across TCGA cell cohorts, MAP1S mutation is significantly associated with the RNA expression of many other genes, with 2,431 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAP1S-associated genes across cancer lineages are GOT2, VPS53, and NUTM1. Each is linked with MAP1S in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP1S-to-partner and partner-to-MAP1S results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOT2 grouped by MAP1S-low versus MAP1S-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1S→partner) and Y-score (partner→MAP1S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GOT2 →	+0.629	+2.364	<.001	<.001	3	3
LARGE_INTESTINE	VPS53 →	+0.748	+3.459	<.001	<.001	3	3
SKIN	NUTM1 →	+0.015	+4.459	.005	.003	3	2
BLOOD_Leukemia	PLEKHA1 →	+1.212	+2.029	<.001	.002	3	2
BLOOD_Leukemia	BBS9 →	+0.627	+1.759	<.001	.007	3	2
BLOOD_Leukemia	FAM98C →	+0.508	+2.518	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,431 associations by consensus.

GOT2 by MAP1S expression — LARGE_INTESTINE

Explore this box plot interactively →