MAP1S

Across TCGA pan-cancer cohorts, MAP1S RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated MAP1S data layer compared with 4 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher MAP1S RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MAP1S expression acts as an unfavorable survival marker, although some lineages such as SCLC and UCS show a favorable association.

SCLC, ACC, and KIRP are the cancer types where MAP1S RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Tertile	All	0.777	0.417	<.001	101	view →
ACC	DFS	Median	All	0.276	0.632	<.001	84	view →
KIRP	DFS	Median	All	0.801	0.905	.008	46	view →
BLCA	OS	Median	All	0.461	0.696	.004	44	view →
LIHC	DFS	Quartile	All	0.427	0.627	<.001	40	view →
LUSC	DFS	Median	III,IV	0.417	0.996	.001	24	view →
UCS	DFS	Median	IV	0.850	0.475	.023	20	view →
OV	OS	Quartile	III,IV	0.603	0.719	.014	16	view →
HNSC	DFS	Quartile	IV	0.436	0.211	.005	14	view →
CESC	OS	Median	IV	0.685	0.108	.009	12	view →
COAD	DFS	Median	IV	0.357	0.605	.004	10	view →
LGG	DFS	Quartile	All	0.347	0.576	.001	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

MAP1S–SCLC (DFS)

Open the SCLC breakdown →