MAP1S

Across TCGA pan-cancer cohorts, MAP1S RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MAP1S’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MAP1S RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MAP1S is over-expressed in tumor.

KIRC, KIRP, and COAD are the cancer types where MAP1S tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAP1S RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.830	<.001	12	view →
KIRP	All	III,IV	+0.844	<.001	11	view →
COAD	Female	All	+0.777	<.001	11	view →
LIHC	Female	II,III,IV	+1.270	<.001	9	view →
HNSC	Male	III,IV	+1.083	<.001	9	view →
STAD	Male	II,III,IV	+1.169	<.001	8	view →
THCA	Male	All	+0.482	<.001	8	view →
BRCA	All	All	+0.268	.005	4	view →
CHOL	Male	All	+2.251	<.001	3	view →
ESCA	All	All	+1.162	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MAP1S–KIRC

Open the KIRC breakdown →