MAN1A1

Across TCGA patient cohorts, MAN1A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,128 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAN1A1-associated proteins across cancer lineages are SLC25A5, LRPPRC, and WDR43. Each is linked with MAN1A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAN1A1-to-partner and partner-to-MAN1A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAN1A1 versus SLC25A5 in BRCA, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN1A1→partner) and Y-score (partner→MAN1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC25A5 →	-0.619	-1.193	<.001	<.001	3	7
HNSC	LRPPRC →	-0.494	-0.874	<.001	.002	3	7
OV	WDR43 →	-0.399	-1.336	<.001	<.001	3	7
GBM	WIPF1 →	+0.433	+1.278	<.001	<.001	3	7
LSCC	CLPX →	-0.335	-0.789	<.001	<.001	3	7
HNSC	ESF1 →	-0.467	-0.836	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,128 associations by consensus.

MAN1A1 vs SLC25A5 — BRCA

Explore this scatter interactively →