MAGEA9B

Across TCGA patient cohorts, MAGEA9B mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA9B-associated genes across cancer lineages are MIR425, RNU4-58P, and RNY4P27. Each is linked with MAGEA9B in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA9B-to-partner and partner-to-MAGEA9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR425 grouped by MAGEA9B-low versus MAGEA9B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA9B→partner) and Y-score (partner→MAGEA9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR425 →	+0.813	+3.914	<.001	.002	3	1
UCEC	RNU4-58P →	+0.393	+4.133	<.001	.002	3	1
UCEC	RNY4P27 →	+0.249	+4.453	.001	.006	3	1
UCEC	LINC02520 →	+0.288	+4.016	<.001	.003	3	1
UCEC	RNU6-342P →	+0.450	+3.418	.001	.009	3	1
UCEC	MIR625 →	+0.317	+4.335	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

MIR425 by MAGEA9B expression — UCEC

Explore this box plot interactively →