MAGEA9B

Across TCGA pan-cancer cohorts, MAGEA9B RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MAGEA9B data layer compared with 1 for mutation status.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher MAGEA9B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MAGEA9B expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

STAD, COAD, and MESO are the cancer types where MAGEA9B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Quartile	IV	0.163	0.694	.003	56	view →
COAD	DFS	Tertile	All	0.305	0.549	.001	51	view →
MESO	OS	Tertile	IV	0.077	0.638	<.001	48	view →
CESC	DFS	Tertile	II,III,IV	0.224	0.533	.014	36	view →
BRCA	OS	Tertile	IV	0.224	0.785	.005	36	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
SARC	OS	Tertile	All	0.608	0.767	.008	18	view →
KIRP	DFS	Tertile	III,IV	0.229	0.731	.005	18	view →
LIHC	OS	Tertile	All	0.633	0.802	.004	18	view →
PRAD	OS	Tertile	All	0.856	0.992	<.001	18	view →
SKCM	DFS	Tertile	All	0.676	0.595	.017	17	view →
ESCA	DFS	Tertile	IV	0.692	0.242	.024	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MAGEA9B–STAD (OS)

Open the STAD breakdown →