MACIR

Across TCGA patient cohorts, MACIR protein abundance is significantly associated with the RNA expression of many other genes, with 3,969 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MACIR-associated genes across cancer lineages are BEND6, C10orf55, and MTURN. Each is linked with MACIR in more than 2 cancer types. Because this analysis shows association rather than direction, both MACIR-to-partner and partner-to-MACIR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACIR versus BEND6 in LUAD, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MACIR→partner) and Y-score (partner→MACIR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BEND6 →	-0.871	-0.464	<.001	.006	3	3
LUAD	C10orf55 →	-1.094	-0.582	<.001	.001	3	3
GBM	MTURN →	+1.352	+0.388	<.001	<.001	3	3
OV	ZC3H10 →	+0.524	+0.498	.006	.002	3	2
OV	MBLAC2 →	+0.730	+0.412	.002	.006	3	2
LUAD	CALHM1 →	-0.128	-0.503	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,969 associations by consensus.

MACIR vs BEND6 — LUAD

Explore this scatter interactively →