chromosome 10 putative open reading frame 55Genealiases: []
Q-omics provides the consensus-scored C10orf55 profile across patient tissues and cancer cell-line models. C10orf55 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, C10orf55 is differentially expressed in 14, with the highest sampling consensus in HNSC. Additionally, C10orf55 RNA expression shows 15,748 significant gene co-expression associations, with the highest sampling consensus in LIHC. Together, these results highlight MESO, HNSC, and LIHC as cancer lineages where C10orf55 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C10orf55 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C10orf55 survival associations across molecular data types. C10orf55 RNA expression shows survival associations in the most cancer types (25), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C10orf55 RNA expression–survival associations across cancer types. High C10orf55 expression shows unfavorable associations in MESO, LGG, BRCA, LUSC and KIRC, but favorable associations in UCS. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for C10orf55 RNA expression.
This table summarizes C10orf55 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for C10orf55. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C10orf55 shows lower tumor expression in KIRC and KIRP and higher tumor expression in HNSC, THCA, COAD and LUAD. The HNSC box plot shows higher C10orf55 RNA expression in tumor versus normal tissue (log2 FC = +1.491, t-test p < 0.001).
This table shows molecular features associated with C10orf55 in patient tissues and cancer cell lines. In patient samples, C10orf55 shows the broadest associations at the RNA and protein expression levels, with LIHC recurring as the lineage with the largest associated feature set. In cancer cell lines, C10orf55 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia, while CRISPR and shRNA rows add functional-dependency signals in URINARY_TRACT and BONE.
