LUARIS

Across TCGA patient cohorts, LUARIS RNA expression is significantly associated with the protein abundance of many other proteins, with 12,877 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LUARIS-associated proteins across cancer lineages are LRP1, FHL3, and THBS2. Each is linked with LUARIS in more than 5 cancer types. Because this analysis shows association rather than direction, both LUARIS-to-partner and partner-to-LUARIS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LUARIS versus LRP1 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LUARIS→partner) and Y-score (partner→LUARIS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LRP1 →	+0.622	+0.180	<.001	.001	3	6
OV	FHL3 →	+0.875	+0.155	<.001	<.001	3	6
OV	THBS2 →	+1.430	+0.156	<.001	.006	3	5
BRCA	VIM →	+0.441	+0.162	<.001	<.001	3	5
LUAD	SETD7 →	+0.298	+0.331	<.001	<.001	3	5
PDAC	SGCE →	+0.418	+0.370	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,877 associations by consensus.

LUARIS vs LRP1 — OV

Explore this scatter interactively →