lncRNA upregulator of antiviral response interferon signalingGenealiases: SCAT6 · lncRNA32
Q-omics provides the consensus-scored LUARIS profile across patient tissues and cancer cell-line models. LUARIS expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LUARIS is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, LUARIS RNA expression shows 12,877 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight KIRC, HNSC, and GBM as cancer lineages where LUARIS shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LUARIS — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LUARIS survival associations across molecular data types. LUARIS RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LUARIS RNA expression–survival associations across cancer types. High LUARIS expression shows unfavorable associations in KIRC, KICH, MESO, THCA, STAD and UVM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LUARIS RNA expression.
This table summarizes LUARIS tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LUARIS. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LUARIS shows lower tumor expression in BRCA, THCA and KICH and higher tumor expression in HNSC, LUAD and LUSC. The HNSC box plot shows higher LUARIS RNA expression in tumor versus normal tissue (log2 FC = +1.190, t-test p < 0.001).
This table shows molecular features associated with LUARIS in patient tissues and cancer cell lines. In patient samples, LUARIS shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
