LRRC75A

Across TCGA patient cohorts, LRRC75A mutation is significantly associated with the RNA expression of many other genes, with 1,304 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC75A-associated genes across cancer lineages are BNIP3P41, LINC02274, and IGHV3OR16-8. Each is linked with LRRC75A in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC75A-to-partner and partner-to-LRRC75A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P41 grouped by LRRC75A-low versus LRRC75A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC75A→partner) and Y-score (partner→LRRC75A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BNIP3P41 →	+0.051	+6.149	<.001	<.001	3	2
COAD	LINC02274 →	+0.080	+4.000	.007	.006	3	2
UCEC	IGHV3OR16-8 →	+0.593	+2.428	.004	.001	3	1
UCEC	CCL5 →	+1.481	+3.716	<.001	<.001	3	1
UCEC	IGKV1OR2-6 →	+0.747	+2.225	.002	.002	3	1
UCEC	DOC2B →	-1.064	-2.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,304 associations by consensus.

BNIP3P41 by LRRC75A expression — COAD

Explore this box plot interactively →