LNCOG

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LNCOG RNA expression is significantly associated with the protein abundance of many other proteins, with 14,526 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LNCOG-associated proteins across cancer lineages are ACTN1, CNN2, and FKBP7. Each is linked with LNCOG in more than 6 cancer types. Because this analysis shows association rather than direction, both LNCOG-to-partner and partner-to-LNCOG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LNCOG versus ACTN1 in OV, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LNCOG→partner) and Y-score (partner→LNCOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVACTN1 →+0.548+0.652<.001<.00137
OVCNN2 →+0.967+0.764<.001<.00137
OVFKBP7 →+0.564+0.603<.001<.00137
LSCCZYX →+0.434+0.397<.001<.00136
COADRCN3 →+0.739+0.299<.001<.00136
OVITIH2 →+1.011+0.609<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,526 associations by consensus.

LNCOG vs ACTN1 — OV

Per-sample scatter of LNCOG vs ACTN1 in OV (Pearson r = 0.71).

Explore this scatter interactively →

Exploration