LNCOG

Across TCGA pan-cancer cohorts, LNCOG RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated LNCOG data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LNCOG RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LNCOG expression acts as an unfavorable survival marker, although some lineages such as THCA and SKCM show a favorable association.

KIRC, STAD, and LGG are the cancer types where LNCOG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.542	0.711	<.001	126	view →
STAD	OS	Median	All	0.361	0.738	<.001	90	view →
LGG	OS	Median	All	0.373	0.534	<.001	54	view →
CESC	DFS	Tertile	All	0.409	0.618	.003	42	view →
LUSC	DFS	Median	All	0.293	0.460	<.001	40	view →
THCA	DFS	Median	II,III,IV	0.910	0.439	.002	39	view →
HNSC	OS	Tertile	All	0.678	0.807	.001	39	view →
GBM	DFS	Median	All	0.173	0.403	<.001	30	view →
MESO	OS	Median	All	0.436	0.645	.005	27	view →
SKCM	OS	Quartile	II,III,IV	0.322	0.199	.007	18	view →
SARC	DFS	Median	All	0.545	0.676	.002	18	view →
KIRP	DFS	Median	II,III,IV	0.283	0.703	.017	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

LNCOG–KIRC (OS)

Open the KIRC breakdown →