Q-omics provides the consensus-scored LINGO1-AS2 profile across patient tissues and cancer cell-line models. LINGO1-AS2 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, LINGO1-AS2 RNA expression shows 8,522 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight STAD, and GBM as cancer lineages where LINGO1-AS2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes LINGO1-AS2 survival associations across molecular data types. LINGO1-AS2 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

LINGO1-AS2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	13	STAD (51)	view →

This table ranks reproducible LINGO1-AS2 RNA expression–survival associations across cancer types. High LINGO1-AS2 expression shows unfavorable associations in STAD, COAD, KIRC, UCEC and THCA, but favorable associations in LGG. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify STAD as the clearest survival context for LINGO1-AS2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	II,III,IV	0.142	0.575	.001	51	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
KIRC	DFS	Tertile	IV	0.307	0.633	.024	36	view →
LGG	OS	Tertile	All	0.550	0.426	.004	22	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
THCA	OS	Tertile	II,III,IV	0.255	0.909	.032	18	view →

Pink = unfavorable, green = favorable. all 13 lineages →

LINGO1-AS2-STAD (OS)

Kaplan–Meier survival curve for LINGO1-AS2 RNA expression in STAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with LINGO1-AS2 in patient tissues and cancer cell lines. In patient samples, LINGO1-AS2 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	8,522	GBM (6610)	view →
Function (RNA)	5,791	STAD (4806)	view →