LINGO1-AS2

Across TCGA patient cohorts, LINGO1-AS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,791 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINGO1-AS2-associated GO terms across cancer lineages are Negative regulation of cell projection organization, Protein-RNA complex organization, and Establishment of protein localization to mitochondrial membrane. Each is linked with LINGO1-AS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both LINGO1-AS2-to-partner and partner-to-LINGO1-AS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell projection organization grouped by LINGO1-AS2-low versus LINGO1-AS2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINGO1-AS2→partner) and Y-score (partner→LINGO1-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of cell projection organization →	+0.088	+0.050	<.001	<.001	3	8
STAD	Protein-RNA complex organization →	+0.138	+0.050	<.001	<.001	3	8
STAD	Establishment of protein localization to mitochondrial membrane →	+0.132	+0.051	<.001	<.001	3	7
STAD	Sensory organ morphogenesis →	+0.052	+0.049	<.001	<.001	3	7
STAD	U2-type prespliceosome assembly →	+0.149	+0.048	<.001	<.001	3	7
STAD	Ribosome assembly →	+0.148	+0.053	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,791 associations by consensus.

Negative regulation of cell projection organization by LINGO1-AS2 expression — STAD

Explore this box plot interactively →