LINGO1-AS2

Across TCGA patient cohorts, LINGO1-AS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,522 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LINGO1-AS2-associated proteins across cancer lineages are RBPMS, SQOR, and HDAC2. Each is linked with LINGO1-AS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LINGO1-AS2-to-partner and partner-to-LINGO1-AS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINGO1-AS2 versus RBPMS in GBM, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINGO1-AS2→partner) and Y-score (partner→LINGO1-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBPMS →	-0.514	-0.669	<.001	<.001	3	3
GBM	SQOR →	-0.900	-0.720	<.001	<.001	3	3
BRCA	HDAC2 →	+0.392	+0.033	<.001	.009	2	4
GBM	KDM2B →	+0.339	+0.590	.001	.005	3	3
GBM	LRRFIP1 →	-0.343	-0.533	<.001	<.001	3	3
UCEC	PAPSS2 →	-0.465	-0.814	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,522 associations by consensus.

LINGO1-AS2 vs RBPMS — GBM

Explore this scatter interactively →