LINGO1-AS1

Across TCGA patient cohorts, LINGO1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,237 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LINGO1-AS1-associated proteins across cancer lineages are ARID1B, CTTNBP2NL_S568, and PRAM1_S298. Each is linked with LINGO1-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LINGO1-AS1-to-partner and partner-to-LINGO1-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINGO1-AS1 versus ARID1B in GBM, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINGO1-AS1→partner) and Y-score (partner→LINGO1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARID1B →	+0.188	+0.495	<.001	.002	3	3
CCRCC	CTTNBP2NL_S568 →	+0.867	+0.097	.002	.009	3	3
LSCC	PRAM1_S298 →	-0.722	-0.093	<.001	.003	3	3
GBM	PSD4 →	-0.368	-0.497	<.001	<.001	3	3
GBM	EVI2B →	-0.492	-0.463	<.001	<.001	3	3
GBM	GNAI1 →	+0.697	+0.577	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,237 associations by consensus.

LINGO1-AS1 vs ARID1B — GBM

Explore this scatter interactively →