long intergenic non-protein coding RNA 2428Genealiases: []
Q-omics provides the consensus-scored LINC02428 profile across patient tissues and cancer cell-line models. LINC02428 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, LINC02428 is differentially expressed in 10, with the highest sampling consensus in HNSC. Additionally, LINC02428 RNA expression shows 10,335 significant protein co-abundance associations, with the highest sampling consensus in HNSC. Together, these results highlight COAD, and HNSC as cancer lineages where LINC02428 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02428 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02428 survival associations across molecular data types. LINC02428 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02428 RNA expression–survival associations across cancer types. High LINC02428 expression shows unfavorable associations in COAD, UVM, KIRC, KICH and CHOL, but favorable associations in BRCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for LINC02428 RNA expression.
This table summarizes LINC02428 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02428. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02428 shows lower tumor expression in LIHC and CHOL and higher tumor expression in HNSC, LUSC, COAD and STAD. The HNSC box plot shows higher LINC02428 RNA expression in tumor versus normal tissue (log2 FC = +1.854, t-test p < 0.001).
This table shows molecular features associated with LINC02428 in patient tissues and cancer cell lines. In patient samples, LINC02428 shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set.
