Q-omics provides the consensus-scored LINC00326 profile across patient tissues and cancer cell-line models. LINC00326 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LINC00326 is differentially expressed in 3, with the highest sampling consensus in THCA. Additionally, LINC00326 RNA expression shows 6,253 significant pathway-activity associations, with the highest sampling consensus in SKCM. Together, these results highlight KIRC, THCA, and SKCM as cancer lineages where LINC00326 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00326 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00326 survival associations across molecular data types. LINC00326 RNA expression shows survival associations in the most cancer types (18), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00326 RNA expression–survival associations across cancer types. High LINC00326 expression shows unfavorable associations in KIRC, ACC, STAD, LIHC, BLCA and UCEC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LINC00326 RNA expression.
This table summarizes LINC00326 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00326. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00326 shows lower tumor expression in THCA and LUSC and higher tumor expression in LUAD. The THCA box plot shows higher LINC00326 RNA expression in normal versus tumor tissue (log2 FC = −0.014, t-test p < 0.001).
This table shows molecular features associated with LINC00326 in patient tissues and cancer cell lines. In patient samples, LINC00326 shows the broadest associations at the RNA and protein expression levels, with SKCM recurring as the lineage with the largest associated feature set. In cancer cell lines, LINC00326 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SOFT_TISSUE, while CRISPR and shRNA rows add functional-dependency signals in STOMACH.
