LINC00326

Across TCGA patient cohorts, LINC00326 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00326-associated genes across cancer lineages are RNU6-340P, PPIAL4F, and CHAC1. Each is linked with LINC00326 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00326-to-partner and partner-to-LINC00326 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-340P grouped by LINC00326-low versus LINC00326-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00326→partner) and Y-score (partner→LINC00326) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-340P →	+0.249	+3.612	<.001	.003	3	2
UCEC	PPIAL4F →	+0.067	+2.646	<.001	.009	3	2
UCEC	CHAC1 →	+1.059	+3.332	.001	.005	3	1
UCEC	NDST4 →	+0.179	+2.928	.003	.005	3	1
UCEC	GLRX5P1 →	+0.521	+3.562	.002	.003	3	1
UCEC	POTEI →	+0.043	+3.759	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

RNU6-340P by LINC00326 expression — UCEC

Explore this box plot interactively →