LINC00326

Across TCGA patient cohorts, LINC00326 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00326-associated genes across cancer lineages are 14-3-3_beta, ACC_pS79, and HSP70. Each is linked with LINC00326 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00326-to-partner and partner-to-LINC00326 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by LINC00326-low versus LINC00326-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00326→partner) and Y-score (partner→LINC00326) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.174	-2.973	.002	.035	3	1
UCEC	ACC_pS79 →	+0.489	+3.000	.014	.037	3	1
UCEC	HSP70 →	-0.464	-3.000	.045	.037	3	1
UCEC	mTOR_pS2448 →	+0.178	+3.000	.039	.037	3	1
UCEC	Stathmin →	-0.164	-3.000	.038	.037	3	1
UCEC	Tuberin_pT1462 →	+0.567	+3.009	<.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

14-3-3_beta by LINC00326 expression — UCEC

Explore this box plot interactively →