long intergenic non-protein coding RNA 200Genealiases: C10orf139 · NCRNA00200
Q-omics provides the consensus-scored LINC00200 profile across patient tissues and cancer cell-line models. LINC00200 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, LINC00200 is differentially expressed in 4, with the highest sampling consensus in LIHC. Additionally, LINC00200 RNA expression shows 9,549 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight KIRP, LIHC, and GBM as cancer lineages where LINC00200 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00200 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00200 survival associations across molecular data types. LINC00200 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00200 RNA expression–survival associations across cancer types. High LINC00200 expression shows unfavorable associations in KIRP, ACC, LIHC, CESC and BRCA, but favorable associations in SKCM. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for LINC00200 RNA expression.
This table summarizes LINC00200 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in READ for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00200. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00200 shows lower tumor expression in KIRC, COAD and READ and higher tumor expression in LIHC. The LIHC box plot shows higher LINC00200 RNA expression in tumor versus normal tissue (log2 FC = +0.101, t-test p = .046).
This table shows molecular features associated with LINC00200 in patient tissues and cancer cell lines. In patient samples, LINC00200 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set. In cancer cell lines, LINC00200 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BREAST, while CRISPR and shRNA rows add functional-dependency signals in LUNG_NSCLC_LUSC.
