LINC-PINT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC-PINT RNA expression is significantly associated with the protein abundance of many other proteins, with 14,939 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LINC-PINT-associated proteins across cancer lineages are RPL12_S38, ARHGEF6, and MCM4_S120. Each is linked with LINC-PINT in more than 5 cancer types. Because this analysis shows association rather than direction, both LINC-PINT-to-partner and partner-to-LINC-PINT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC-PINT versus RPL12_S38 in LSCC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC-PINT→partner) and Y-score (partner→LINC-PINT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRPL12_S38 →-0.974-0.497<.001<.00135
UCECARHGEF6 →+0.390+0.913<.001<.00135
LUADMCM4_S120 →-1.090-0.494.004.00626
HNSCGAN →-0.590-0.750<.001<.00135
UCECRRM2 →-0.630-0.735.003.00434
HNSCSNX2 →+0.303+0.678<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,939 associations by consensus.

LINC-PINT vs RPL12_S38 — LSCC

Per-sample scatter of LINC-PINT vs RPL12_S38 in LSCC (Pearson r = -0.36).

Explore this scatter interactively →

Exploration