LINC-PINT

Across TCGA pan-cancer cohorts, LINC-PINT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated LINC-PINT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC-PINT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC-PINT expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

KIRC, BLCA, and COAD are the cancer types where LINC-PINT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.511	0.740	<.001	119	view →
BLCA	OS	Median	All	0.793	0.641	<.001	115	view →
COAD	DFS	Tertile	All	0.565	0.752	<.001	56	view →
SKCM	OS	Tertile	All	0.406	0.248	<.001	55	view →
KICH	OS	Median	II,III,IV	0.578	1.000	.001	49	view →
ACC	DFS	Median	All	0.435	0.775	.001	45	view →
LUAD	OS	Median	All	0.475	0.263	.005	26	view →
PRAD	DFS	Tertile	All	0.838	0.929	.005	16	view →
PAAD	DFS	Tertile	All	0.394	0.182	.012	15	view →
KIRP	OS	Tertile	II,III,IV	0.093	0.729	.002	15	view →
STAD	DFS	Median	All	0.266	0.472	.006	13	view →
SARC	OS	Quartile	All	0.805	0.612	.002	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

LINC-PINT–KIRC (DFS)

Open the KIRC breakdown →