Q-omics provides the consensus-scored LINC-PINT profile across patient tissues and cancer cell-line models. LINC-PINT expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LINC-PINT is differentially expressed in 10, with the highest sampling consensus in COAD. Additionally, LINC-PINT RNA expression shows 19,171 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, COAD, and UVM as cancer lineages where LINC-PINT shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC-PINT — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC-PINT survival associations across molecular data types. LINC-PINT RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC-PINT RNA expression–survival associations across cancer types. High LINC-PINT expression shows unfavorable associations in KIRC, COAD, KICH and ACC, but favorable associations in BLCA and SKCM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LINC-PINT RNA expression.
This table summarizes LINC-PINT tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for LINC-PINT. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC-PINT shows lower tumor expression in LUSC, THCA, UCEC and BRCA and higher tumor expression in COAD and LIHC. The COAD box plot shows higher LINC-PINT RNA expression in tumor versus normal tissue (log2 FC = +1.049, t-test p < 0.001).
This table shows molecular features associated with LINC-PINT in patient tissues and cancer cell lines. In patient samples, LINC-PINT shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
