LHX5-AS1

Across TCGA patient cohorts, LHX5-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,847 significant associations in total. LGG shows the largest number of these associations.

The most reproducible LHX5-AS1-associated GO terms across cancer lineages are Regulation of synapse assembly, Arterial endothelial cell differentiation, and Regulation of synaptic vesicle cycle. Each is linked with LHX5-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LHX5-AS1-to-partner and partner-to-LHX5-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synapse assembly grouped by LHX5-AS1-low versus LHX5-AS1-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHX5-AS1→partner) and Y-score (partner→LHX5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Regulation of synapse assembly →	+0.030	+0.766	<.001	<.001	3	6
TGCT	Arterial endothelial cell differentiation →	+0.068	+0.920	<.001	.001	3	6
LGG	Regulation of synaptic vesicle cycle →	+0.053	+0.962	<.001	<.001	3	6
TGCT	Mechanoreceptor differentiation →	+0.021	+0.920	<.001	<.001	3	6
UCS	NADH dehydrogenase complex assembly →	+0.041	+0.052	.005	.009	1	7
LGG	Cytolysis →	-0.084	-1.269	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,847 associations by consensus.

Regulation of synapse assembly by LHX5-AS1 expression — GBM

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