LENEP

Across TCGA patient cohorts, LENEP RNA expression is significantly associated with the protein abundance of many other proteins, with 14,994 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LENEP-associated proteins across cancer lineages are DSN1, OTUD7B, and RPRD2. Each is linked with LENEP in more than 5 cancer types. Because this analysis shows association rather than direction, both LENEP-to-partner and partner-to-LENEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LENEP versus DSN1 in GBM, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LENEP→partner) and Y-score (partner→LENEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DSN1 →	+0.430	+0.556	<.001	<.001	3	6
BRCA	OTUD7B →	+0.330	+0.544	<.001	<.001	3	6
HNSC	RPRD2 →	+0.297	+0.805	<.001	<.001	3	5
LSCC	BRD8 →	+0.255	+0.665	<.001	<.001	3	5
UCEC	CDC73 →	+0.269	+0.680	<.001	<.001	3	5
LSCC	DHX9 →	+0.278	+0.832	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,994 associations by consensus.

LENEP vs DSN1 — GBM

Explore this scatter interactively →