KRTAP7-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP7-1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP7-1-associated genes across cancer lineages are RNU6-591P and RN7SL495P. Each is linked with KRTAP7-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP7-1-to-partner and partner-to-KRTAP7-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-591P grouped by KRTAP7-1-low versus KRTAP7-1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP7-1→partner) and Y-score (partner→KRTAP7-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-591P →+0.547+8.066<.001.00731
COADRN7SL495P →+0.158+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

RNU6-591P by KRTAP7-1 expression — UCEC

Box plot of RNU6-591P in KRTAP7-1-low vs KRTAP7-1-high samples in UCEC.

Explore this box plot interactively →

Exploration